Cedric the Entertainer, Jhené Aiko, Kings of Leon

Machine Gun Kelly, Mamoudou Athie

Special Guest Host Demi Lovato – Justin Bieber, Jhené Aiko, Miguel, and Future

Guest Host tWitch, Randall Park, Allison Holker Boss, Zara Larsson

Demi Lovato, Justin Bieber Performs

Paul Bettany, Maluma

David Beckham, Usher, a Performance by Justin Bieber and Quavo

Guest Host Mickey Guyton with Jimmie Allen, Priscilla Block

Melissa McCarthy & Octavia Spencer, Kristen Bell & Dax Shepard, Brandy Clark

Sen. Elizabeth Warren, Khalid, Justin Bieber

Kevin Nealon, Jacob Elordi

Eddie Murphy, Bella Murphy, Rapper The Kid LAROI